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Author

Zhaohua Shi

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Sep 2026

TPGS-functionalized liposomal formulation for the transdermal delivery of ellagic acid.

The pursuit of effective anti-aging interventions remains a significant challenge in dermatological research. Ellagic acid (EA), a natural polyphenol with demonstrated anti-skin-aging properties, faces limitations in therapeutic application due to poor percutaneous absorption. To address this challenge, we developed TP...

Xiao-Jing Yang, Zhi Dong, Lei Xu et al. · 0 citations
Jul 2026

Identification of allosteric sites and allosteric inhibitors in the glucose-dependent insulinotropic polypeptide receptor via molecular simulations.

This study provides potential lead compounds for the design of small-molecule allosteric drugs targeting class B1 GPCRs and performs conformational sampling and combined dynamic pocket detection algorithms, MDpocket and FTMove, to identify six characteristic cryptic pockets within the dynamic trajectories.

Zhi Dong, Long Cheng, Qingxin Shi et al. · 0 citations

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