Zhaomeng Chen

CIT-Lasso: a scalable approach beyond guilty by association for identifying causal variants from genome-wide summary statistics

We present CIT-Lasso, a framework that uses only summary statistics to identify, genome-wide, sets of variants carrying non-redundant information on a phenotype, distinguishing likely causal variants from correlated variants that are merely associated. The open-source implementation completes genome-wide analysis in un...