Review
Open access
Sep 2026
CAR-based therapies in systemic autoimmunity: from deep immune depletion toward durable immune reset.
It is argued that future progress will require tissue-validated, clonally resolved and functionally informed definitions of therapeutic success, and a three-tier framework for immune reset after CAR-based therapy is proposed: serological reset, cellular reset and homeostatic reset.
Hong-Yu Zhang, Bai-Xiu Wu, Heng-Quan Wan et al.
· International Immunopharmaco... · 0 citations