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Author

Zhe-Yu Fang

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Sep 2026

Betulin supplementation reduces oxidative stress in Alzheimer's disease via the activation of KEAP1/NRF2 pathway.

Betulin (BE) is extracted from pentacyclic triterpenoids of many natural plants and has antioxidation activities. However, the neuroprotective effects and underlying mechanism of Betulin in Alzheimer's disease (AD) have remained limited. Integrate SuperPred, SEA, and Targeted Net databases, as well as KEGG pathway enri...

Cong-Hui Dai, Yao Yang, Xia-Oou Lin et al. · 0 citations
Open access Aug 2026

Electroporation-primed cascade nanocatalysis boosts STING-driven chemoimmunotherapy in hepatocellular carcinoma

Nanosecond pulsed electric field (nsPEF) ablation enables non-thermal tumor destruction with favorable tissue selectivity, but its long-term efficacy is often limited by postoperative recurrence. Here, we developed an electroporation-primed, tumor microenvironment-responsive core-shell cascade nanoparticle, ZnO2-NiFc@M...

Jia-Xin Zhao, Zhe-Yu Fang, Zi-Wei Luo et al. · 0 citations

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