Zhe-Yu Niu

Hrd1 alleviates fatty liver ischemia-reperfusion injury by regulating the phenotypic polarization of Kupffer cells.

To address the persistent shortage of donor livers for transplantation, steatotic grafts are increasingly being accepted as marginal allografts. However, fatty liver is highly susceptible to ischemia-reperfusion injury (IRI), leading to high post-transplant graft dysfunction rates, with no effective alleviation methods...