Review
Open access
Sep 2026
Deep brain stimulation mechanisms in comorbid pain and emotional dysregulation from animal models
This mechanism-based framework outlines a translational roadmap for personalized neuromodulation, guiding symptom-specific target selection and the development of biomarker-driven, closed-loop DBS systems to concurrently treat pain and affective pathologies.
Tian-En Si, Hao Han, Ying-Ying Zhang et al.
· iScience · 0 citations