Pd-Catalyzed Asymmetric Tandem Allylic Alkylation/Etherification: Enantioselective Access to Medium-Sized Oxa-spirocycles
Pd-catalyzed asymmetric tandem allylic substitution has proven to be a powerful strategy for constructing chiral rings; however, its application to chiral medium-sized spirocyclic systems remains undeveloped. Herein, we report a Pd-catalyzed asymmetric tandem allylic alkylation/etherification that enables efficient a...