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Author

Zhen-Jie Wang

2 papers indexed here

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Review Open access Aug 2026

Metabolite-driven protein modifications in immune signaling: from established principles to emerging pyruvylation

The conceptual framework of metabolite-driven protein modifications is summarized, established marks are compared, and remaining questions surrounding pyruvylation chemistry, enzyme and substrate specificity, reader mechanisms, compartmentalization, detection strategies, physiological relevance, and potential immunopha...

Zi-Ye Zhang, Ming-Ze Xu, Sen Zhang et al. · 0 citations
Open access Aug 2026

Optimizing vancomycin therapy: the critical role of dosing frequency, AUC monitoring and gender: a retrospective cohort study

Traditional PK/PD targets (Ctrough and AUC/MIC) did not correlate with clinical efficacy in this real-world setting, and AUC was a better predictor of nephrotoxicity than Ctrough, and female gender was an independent risk factor for vancomycin-associated anemia.

Nai-Ju Zhang, Yi Li, Long-Yun Chen et al. · 0 citations

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