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Review Oct 2026

α-Lipoic acid: from a mitochondrial cofactor to a versatile platform for dynamic biomaterials and translational biomedicine.

α-Lipoic acid (LA) is a naturally occurring small molecule possessing both endogenous cofactor activity and dynamic covalent polymerization capability. The 1,2-dithiolane ring in its structure enables both redox-responsive biological functions and ring-opening polymerization to yield polylipoic acid (PolyLA) with a dyn...

Chun-Yan Cui, Chen-Xi Zheng, Zhen Liu et al. · 0 citations

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