Open access
Sep 2026
A little longer, a lot better: simulation-guided exploration of extended-length single-end barcoded reads for structural variant detection
Abstract Motivation Accurate detection of genetic variants, including single nucleotide polymorphisms (SNPs), small insertions and deletions (INDELs), and structural variants (SVs), is essential for comprehensive genomic analysis. While short-read sequencing performs well for SNP and INDEL detection, it remains limited...
Can Luo, Y. Liu, Han Liu et al.
· Bioinformatics Advances · 0 citations