SRC Promotes High Glucose-Induced Retinal Endothelial Dysfunction by Suppressing FUNDC1-Mediated Mitophagy in Diabetic Retinopathy.
PURPOSE Diabetic retinopathy (DR) is a leading cause of blindness, yet the role of mitophagy in its pathogenesis remains unclear. This study aims to dissect mitophagy heterogeneity in DR at single-cell resolution and identify key regulators. METHODS Bulk RNA-seq datasets were first used to screen mitophagy-related ge...