Author

Zhen Zhang

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Open access Sep 2026

FKAN-MoCBDTI: Multimodal drug-target interaction prediction via collaborative bilinear attention and knowledge distillation.

Drug-target interaction (DTI) prediction plays a pivotal role in drug discovery and drug repurposing, yet current deep learning approaches still suffer from limitations in multimodal fusion, fine-grained cross-modal interaction modeling, nonlinear representation learning, and inductive generalization. To overcome these...

Xian-Jun Hu, Zhen Zhang, Zi-Yan Deng et al. · Computational biology and ch... · 0 citations

Open access Sep 2026

A Graph Convolutional Network Framework Integrating Nuclear Norm Minimization and Conditional Random Fields for Microbe–Disease Association Prediction

A novel predictive model, NNGCFCAE is proposed, which integrates Nuclear Norm Minimization (NNM), an enhanced Graph Convolutional Network (GCF) with an energy-based Conditional Random Field (CRF) smoothing mechanism, and a multi-channel convolutional autoencoder (CAE) with residual connections to effectively infer late...

Zhen Zhang, Xiang-Jun Hu, Jia-Cheng Lai et al. · Algorithms · 0 citations