Author

Zhe-Nan Zhang

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Open access Oct 2026

Macrophage pyroptosis drives luminal senescence and club-cell reprogramming in 5α-reductase inhibitor-treated prostatic hyperplasia.

Benign prostatic hyperplasia (BPH) is a common age-associated disease whose prevalence rises sharply with advancing age. Therapeutic responses to 5α-reductase inhibitors (5-ARIs) in BPH are heterogeneous and may ultimately culminate in the need for surgery; however, the mechanisms that permit disease progression during...

Zheng Li, Zhe-Nan Zhang, Qian-Cheng Zhao et al. · Experimental and Molecular M... · 0 citations

Open access Aug 2026

Single-cell transcriptomic landscape of metabolic reprogramming in kidney allograft rejection

A single-cell atlas of metabolic states in healthy and transplanted human kidney samples offers novel insights into the heterogeneous nature of rejection and provides valuable guidance for the development of targeted therapies.

Zhenan Zhang, Yi-Chun Zheng, Long Zheng et al. · Frontiers in Immunology · 0 citations