Endometrial decidualization is a hormonally programmed differentiation and tissue-remodeling process that prepares the endometrium for embryo implantation and supports early pregnancy. It involves coordinated changes in endometrial stromal cells, the extracellular matrix, vascular function, metabolism, and local immune...
Simple Summary 3-Nitropropionic acid (3-NPA) is a mitochondrial toxin that inhibits succinate dehydrogenase and can cause reproductive and ovarian injury. Although direct studies have shown that 3-NPA exposure can increase oxidative stress, impair mitochondrial function, promote granulosa-cell apoptosis, disrupt follic...
Zheng-Hong Zhang, De-Fan Wang, Qing-He Lin et al.· Biology· 0 citations
A hypothesis-driven framework is proposed in which NLRP3 may act as a candidate redox-metabolic integrative node that coordinates stress-related signals within the follicular microenvironment and may contribute to developmental transitions including follicular growth, dominance acquisition, ovulatory competence, and at...
Zheng-Hong Zhang, De-Fan Wang, Qing-Qiang Lin et al.· Frontiers in Cell and Develo...· 0 citations
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