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Zheng-Han Dong

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Sep 2026

Synthesis of Axially and Centrally Chiral Alkylidenecyclobutanes Enabled by Catalytic Enantioselective Allylboration

A chiral phosphoric acid catalyzes asymmetric allylboration of stereodefined alkenylcyclobutyl boronates with aldehydes, constructing alcohol-functionalized alkylidenecyclobutanes (ACBs) bearing both axial and central chirality. The reaction proceeds under mild conditions with broad scope, affording products in high...

Kun Liu, Zheng-Han Dong, Dao-Jin Ruan et al. · 0 citations

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