Permissive but not causative: layer-specific LHCGR alterations in ovarian aging
The ovary is among the earliest organs to show clinically consequential age-related decline. The luteinizing hormone/choriogonadotropin receptor (LHCGR) mediates the trophic actions of LH and human chorionic gonadotropin (hCG) in the ovary, and reduced receptor abundance has sometimes been invoked as a possible expla...