Author

Zheng-Hong Qin

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Aug 2026

Cobrotoxin Alleviates Lipopolysaccharide-Induced Depression-like Behavior in mice.

Depression is a debilitating psychiatric disorder closely linked to neuroinflammation. Cobrotoxin (CoTX), an active component of Naja atra venom, exhibits multiple therapeutic effects, including analgesic, anti-inflammatory, and microcirculation-improving properties. However, its role in neuroinflammation-associated de...

Jinchun Qian, Jun-tong Lou, Keke Liu et al. · Toxicon · 0 citations

Aug 2026

Cobrotoxin suppresses TLR4-NF-κB/STAT1 signaling to mitigate glia-mediated neuroinflammation and motor deficits in Parkinson's disease.

Chronic neuroinflammation is implicated in the pathogenesis of Parkinson's disease (PD), contributing to progressive dopaminergic neuron loss. Cobrotoxin (CoTX), a short-chain α-neurotoxin isolated from Naja atra venom, exerts anti-inflammatory and analgesic effects in several inflammation-related disease models. Howev...

Chun-Ze Yu, Shuyang Ma, Yuzhihan Cao et al. · International Immunopharmaco... · 0 citations