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Author

Zheng Song

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Open access Oct 2026

Route-Dependent Behavioral, Dopaminergic, and Transcriptomic Adaptations to Nicotine Aerosol Inhalation and Systemic Injection in Male Mice.

Nicotine is one of the most widely used psychoactive substances, yet most preclinical studies rely on subcutaneous injection, which does not fully model inhalation-based exposure. How different nicotine delivery paradigms shape neurobehavioral adaptations remains unclear. Here, we compared subcutaneous nicotine injecti...

Yu-Nu Ma, Zheng Song, Yi-Bo Chen et al. · 0 citations
Open access Sep 2026

Adult-onset hippocampal α7 nicotinic acetylcholine receptor loss rapidly drives Alzheimer-like neuropathology in mice

Introduction The reduction of α7 nicotinic acetylcholine receptor (nAChR) in the hippocampus con-stitutes one of the neuropathological features observed in the brains of individuals with Alzheimer’s disease (AD), and α7 nAChR is crucial to cognitive process. However, studies involving α7 nAChR knockout mice have not de...

Jun Li, Guang-Lin Liu, Xiao-Tong Wang et al. · 0 citations

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