Zheng-Ting Zou

Single-cell transcriptomics uncovers conserved cardiac cell types and regulatory adaptation across birds and mammals

Birds and mammals possess highly efficient four-chambered hearts to meet the elevated metabolic demands of endothermy, yet the cellular and molecular basis of this convergent evolution remains poorly understood. To address this gap, we generated the first single-cell heart transcriptomic atlas of a wild bird, the Euras...