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Author

Zheng-Wei Dong

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Sep 2026

Sodium tanshinone IIA sulfonate attenuates pulmonary vascular remodeling by targeting DYRK1A in pulmonary hypertension.

BACKGROUND Pulmonary hypertension (PH) is a progressive disorder marked by elevated pulmonary artery (PA) pressure and vascular remodeling, often leading to right heart failure. A key feature is pulmonary artery smooth muscle cells (PASMC) phenotypic switching from a contractile to a synthetic state, which drives media...

Zheng-Wei Dong, Qian-Qian Lu, Zhi-Feng Xue et al. · 0 citations
Open access Jul 2026

The bidirectional genetic causality between immunocyte phenotypes and dilated cardiomyopathy: A bidirectional Mendelian randomization study

It is indicated that CD28 on secreting regulatory T cell could mitigate the occurrence of DCM, and reciprocally, the progression of DCM could reduce the level of CD28 on secreting regulatory T cell.

Wenshuai Feng, Xindi Chang, Qiaozhi Li et al. · 0 citations

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