Author

Zheng-Wei Zhang

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Open access Dec 2026

CHCHD2 as a prognostic biomarker and therapeutic target in lung adenocarcinoma: Insights from pan‑cancer multi‑omics and functional studies.

Lung adenocarcinoma (LUAD) remains a leading cause of cancer‑related mortality, and mitochondrial proteins have been increasingly implicated in tumor progression. Coiled‑coil‑helix‑coiled‑coil‑helix domain‑containing 2 (CHCHD2) has been reported in several malignancies, yet its pan‑cancer landscape and LUAD‑specific fu...

Zi-Kai Xu, Jie Shen, Yi-Zhou Lin et al. · Oncology Report · 0 citations

Sep 2026

A Magnesium-Phenolic Coordinated Hydrogel Orchestrates Antiapoptotic, Immunomodulatory, and Angiogenic Niches for Aging Wound Regeneration.

Geriatric cutaneous wound healing is impeded by a senescent microenvironment characterized by excessive oxidative stress, persistent inflammation, and impaired vascularization. While conventional therapies are often constrained by suboptimal efficacy in aged skin, emerging biomaterial-based strategies offer promising a...

Peng-Cheng Xu, Ying Su, Zi-Niu Tang et al. · ACS Applied Materials and In... · 0 citations

Review Open access Aug 2026

Mitochondrial homeostasis and aging: the mtDNA-cGAS-STING axis

This review systematically elucidates the molecular basis of the mtDNA-cGAS-STING pathway, delves into its organ-specific activation mechanisms, and critically evaluates current intervention frameworks and clinical prospects, aiming to provide a theoretical basis and innovative perspectives for the precision prevention...

Ling Wang, Zheng-Wei Zhang, Bin-Bin Xia et al. · Frontiers in Immunology · 0 citations