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Author

Zheng-Xuan Jiang

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3 papers indexed here

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Review Sep 2026

Lactylation and oxidative stress in diabetic retinopathy: Emerging links among metabolic reprogramming, epigenetic regulation and therapeutic potential.

Diabetic retinopathy (DR) is a leading cause of visual impairment and is characterized by progressive microvascular injury, neurovascular dysfunction, and sustained oxidative stress. Lactylation, a lactate-derived post-translational modification, may represent a mechanistic link between hyperglycemia-induced metabolic...

Xiao-Yan Liu, Yu Li, Qing Wang et al. · 0 citations
Open access Aug 2026

Lysosomal Membrane Protein SCARB2 Mediates the Pathogenesis of Diabetic Retinopathy Through the MAPK/ERK/MMP9 Signaling Pathway

Diabetic retinopathy (DR), the most prevalent complication of diabetes, remains a major cause of preventable blindness in the working‐age population. Retinal microvascular endothelial cell dysfunction is central to DR pathogenesis, and lysosomal pathways play a key role in regulating endothelial injury. This study aims...

Jiawei Fan, Wei-Qian Cao, Jianghui Wang et al. · 0 citations
Review Open access Sep 2026

Natural antioxidant products and nanomaterial-based delivery systems for the amelioration of diabetic retinopathy: mechanisms, applications, and translational perspectives

Diabetic retinopathy (DR) is a leading global cause of vision loss, closely linked to hyperglycemia-induced oxidative stress, chronic inflammation, and pathological angiogenesis. Natural antioxidants exhibit great therapeutic potential against DR but are severely limited by poor solubility, low bioavailability, and ins...

Yu-Lin Tao, Bing-Xu Zha, Fangpu Zhang et al. · 0 citations

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