Zheng-Xue Quan

An injectable ROS-responsive PRP-loaded hydrogel attenuates osteoarthritis by reducing oxidative stress, inflammation and chondrocyte apoptosis.

Osteoarthritis (OA) is a degenerative joint disease mainly characterized by oxidative stress, inflammatory responses, and loss of cartilage matrix. Although platelet-rich plasma (PRP) has been applied in OA treatment, its intra-articular use is still limited by insufficient local retention and short duration of action....