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Zheng-Zhi Wu

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Review Open access Sep 2026

Modulating the NLRP3/IL-1β Axis in Age-Related Atherosclerosis: Natural Products, Molecular Mechanisms, and Translational Perspectives—A Narrative Review

Atherosclerosis is an age-related immune-metabolic disease in which lipid retention, endothelial dysfunction, innate immune activation, and vascular remodeling interact over decades. In older adults, inflammaging, mitochondrial dysfunction, defective autophagy/mitophagy, and cellular senescence may lower the threshold...

Yelizaveta A. Marakhovskaya, Ksenia A. Eruslanova, O. Maltseva et al. · 0 citations

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