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Author

Zhenhui Lu

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Sep 2026

SOX9 attenuates osteoarthritis bNy regulating autophagy via the PI3K/Akt/mTOR pathway.

The pathogenesis of osteoarthritis (OA) has remained unclear, posing a clinical challenge. Although SRY-box transcription factor 9 (SOX9) has been reported to inhibit OA progression, the specific mechanisms through which it regulates inflammation in OA, especially with respect to chondrocyte autophagy, remain poorly un...

Jun Qin, Zai-Nen Qin, Ke Ma et al. · 0 citations
Open access Jul 2026

NIR-II-activated supramolecular LDH nanoarchitecture integrated with 3D-printed bioactive glass for hypoxia-resistant photodynamic osteosarcoma therapy and bone regeneration

A novel functionalized 3D-printed scaffold with NIR-II responsiveness (BGS/I-LDH@MgO2), designed to simultaneously address the dual needs of inhibiting osteosarcoma recurrence and promoting bone regeneration, demonstrates excellent anti-tumor and osteogenic properties.

Hong Cheng, Tao Wang, Hanji Huang et al. · 0 citations

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