Open access
Aug 2026
NAT10 is critical to block RNA sensing-induced IFN-β transactivation in viral infection
ABSTRACT Cells detect invading viruses and produce type I interferons (IFNs) to stimulate an innate antiviral effector response. However, IFN levels must be fine-tuned to achieve antiviral efficacy while limiting hyperinflammatory and tissue-damaging effects. Here, we report that NAT10, a histone and cytidine acetyltra...
Youngmin Park, Yan Liu, Jinshan He et al.
· mBio · 0 citations