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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Zheyu Zhou

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Jul 2026

GoMA-DTA: A Gene Ontology-Guided Multimodal Attention Fusion Model for Drug-Target Affinity Prediction.

GoMA-DTA is proposed, a framework integrating gene ontology (GO) functional annotations with protein semantic features with channelwise gating mechanism that uses functional semantics as anchors to dynamically recalibrate ESM-2embeddings, achieving adaptive semantic filtering.

An Xiong, Zheyu Zhou, Yazi Li et al. · 0 citations