ETHNOPHARMACOLOGICAL RELEVANCE
Si-Si-Gu-Ben (SSGB), a traditional Chinese medicinal formula derived from the theory of "warming the spleen and kidney to arrest diarrhea," is frequently prescribed for diarrhea-predominant irritable bowel syndrome (IBS-D) in clinical practice, yet its pharmacological mechanisms remain in...
Yun-Jiao Xu, Wen-Di Wu, Zhi-Bi Zhang et al.· Journal of Ethnopharmacology· 0 citations
WD-repeat domain 5 (Wdr5), a core component of the SET1/MLL family of histone methyltransferases, is widely involved in the regulation of development, epigenetic control, transcription, and cell division. Wdr5 has been linked to neurodevelopmental disorders characterized by intellectual disability and developmental del...
Hui-Shan Wang, Wei Li, Peng-Cheng Ma et al.· Journal of Molecular Cell Bi...· 0 citations
These findings integrate population-level, computational, and hepatocyte evidence, suggesting that matrix remodeling, inflammation, and lipid metabolism may underlie the link between BPA exposure and NAFLD.
Jun-Yu Xu, Juqing Deng, Zi-Yue Zhang et al.· Drug and chemical toxicology...· 0 citations
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