Zhi-Han Liao

Lipid droplet-mitochondria mismatch in atherosclerosis: From disrupted lipid routing to persistent inflammation and necrotic core expansion.

Atherosclerosis (AS) is a chronic lipid-driven inflammatory disease of the arterial wall, and substantial cardiovascular risk persists despite intensive lipid-lowering therapy. Plaque progression depends not only on lipid entry, but also on how vascular wall cells handle intracellular lipids under sustained stress. Lip...