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Author

Zhi-Han Wang

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Open access Sep 2026

TFAM Dependent Mitochondrial Fitness Limits CD8⁺ T Cell Immunopathology and Sustains Protective Immunity during Viral Pneumonia

During respiratory virus infection, CD8+ T cells kill infected cells and establish antigen-specific memory, but mechanisms regulating these functions remain incompletely understood. Here, we identify mitochondrial transcription factor A (TFAM)-dependent mitochondrial fitness as a regulator of CD8+ T cell function durin...

Z. Navaeiseddighi, Kai Guo, S. Hasan et al. · 0 citations

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