Open access
Aug 2026
Autoimmune gastritis diverges from a shared corpus origin: molecular reconstruction of the adenocarcinoma axis and clinical anchoring of the neuroendocrine axis
Autoimmune gastritis (AIG) arises from a T-cell–mediated immune attack on the gastric parietal cell and carries a dual neoplastic risk: gastric adenocarcinoma through spasmolytic polypeptide-expressing metaplasia (SPEM) and intestinal metaplasia, and type-1 gastric neuroendocrine tumour (NET) through hypergastrinaemia-...
Jing-Na Tao, Ling-Han Meng, Xiyan Zhang et al.
· Frontiers in Immunology · 0 citations