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Author

Zhi-Hong Yao

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Open access Sep 2026

Mycobacterium tuberculosis Rv0158 negatively regulates the cGAS-STING pathway mediated type I IFN production and enhances intracellular survival.

Overall, the finding identified a new bacterial factor Rv0158, which improves the understanding of the immune evasion mechanisms of M. tb, and suggests that Rv0158 may indirectly facilitate STING degradation or modulate its stability through host-interacting partners.

Zheng-Zhong Xu, Min-Li Geng, Zhi-Hong Yao et al. · 0 citations

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