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Zhi-Jie Xu

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Sep 2026

APOE-centered transcriptional convergence underlying diverse dementia subtypes.

BackgroundDementia subtypes exhibit diverse clinical and pathological features, yet may share convergent molecular underpinnings. Identifying these common pathways is critical for unified therapeutic strategies.ObjectiveTo delineate the shared genetic architecture and convergent molecular pathways underlying diverse de...

Zhi-Jie Xu, Jie Ma, G. M. Giuffré et al. · Journal of Alzheimer's Disea... · 0 citations

Open access Aug 2026

Early functional disconnection of the basal forebrain-hippocampal system predicts memory impairment in amnestic mild cognitive impairment.

Directional connectivity alterations within the BF-hippocampal-cortical axis were observed in patients with aMCI in the absence of detectable macroscopic atrophy, highlighting the potential contribution of BF-related network dysfunction to early disease processes.

Juan-Juan Lu, Zhi-Jie Xu, Jie Ma et al. · Neuroscience · 0 citations