Author

Zhi-Kai Cao

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Open access Sep 2026

Keratinocyte-derived CXCL-CXCR2 ligand-receptor axis by MED1 orchestrates neutrophil phenotypes during psoriasis

Psoriasis is a chronic inflammatory skin disease characterized by aberrant keratinocyte proliferation and dysregulated immune responses. Increasing evidence suggests that reciprocal communication between tissue-resident keratinocytes and infiltrating immune cells shapes the inflammatory microenvironment and governs...

Ying-Xi Li, Jun-Kai Huang, Gui-Xin Wang et al. · Frontiers in Immunology · 0 citations

Open access Aug 2026

Integrative single-cell and genomic analysis reveals NMB as a driver of metastatic adaptation in esophageal squamous cell carcinoma via metabolic rewiring and immune evasion

NMB serves as a key driver of metastatic adaptation in ESCC, conferring a survival advantage to tumor cells during metastatic colonization through genomic evolution and immune remodeling, with metabolic adaptation as a downstream consequence of genomic alterations.

Zhi-Kai Cao, Dong-Chen Tian, Long He et al. · Frontiers in Cell and Develo... · 0 citations