Author

Zhi-Li Guo

2 papers indexed here

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Open access Oct 2026

Mechanisms of action of TNF-α and IL-6 in cancer pain

Cancer pain is a prevalent and often treatment-resistant complication of advanced cancer, highlighting the need for mechanism-based non-opioid targets. Inflammation within the tumor microenvironment is central to cancer pain, with TNF-α and IL-6 consistently implicated across preclinical models. However, these cytoki...

Xin Jin, Jie Liu, Dian-Qun Ren et al. · Frontiers in Pain Research · 0 citations

Review Open access Oct 2026

Mechanisms and targeted intervention strategies of macrophage mitochondrial quality control imbalance in the progression of atherosclerosis

Atherosclerosis (AS) is a vascular disease characterized by lipid accumulation, chronic inflammation, and plaque instability, which can lead to severe cardiovascular events, such as myocardial infarction and stroke. Macrophages are the predominant immune cells within plaques and form foam cells upon uptake of oxidized...

Zhi-Li Guo, Xiao-Yu Zhu · Frontiers in Physiology · 0 citations