Author

Zhiliang Yu

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Open access Sep 2026

Shewanella oneidensis employs both β-lactam resistance and tolerance controlled by the PghKR system

ABSTRACT Antibiotic tolerance enables bacterial survival during antibiotic exposure and can promote the evolution of resistance, thereby threatening therapeutic efficacy. However, the molecular mechanisms underlying tolerance and its relationship with resistance remain incompletely understood. In this study, we show th...

Jing-Xiao Cai, Yan Liang, Yu Chen et al. · mBio · 0 citations

Open access Jul 2026

A double-layer plate method for rapid screening of cell wall-targeting antibiotic producers using a microbial whole-cell biosensor

A high-throughput screening platform integrating a microbial whole-cell biosensor into a double-layer plate assay, enabling rapid identification of bacteria producing cell wall-targeting antibiotics from environmental samples, and accelerating the discovery of novel antibiotic producers from complex environmental commu...

Jianping Xu, Chiheng Gong, Jiaqi Yu et al. · Applied and Environmental Mi... · 0 citations