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Open access Jul 2026

ZC3H13‐mediated m6A stabilization of CCND1 promotes malignant progression and is associated with poor anti‐PD‐1 response in HNSCC

The findings identify ZC3H13 as a potential therapeutic target for improving the efficacy of anti‐PD‐1 treatment in HNSCC and contributes to malignant tumor phenotypes and alterations in immunosuppressvie features.

Wen-Qing Chen, Yun Li, Shuang Chen et al. · 0 citations
Open access Jul 2026

Single-cell and spatial transcriptomic analysis reveal distinct tumor microenvironment signatures in primary and recurrent hypopharyngeal squamous cell carcinoma

A pro-recurrent TME is revealed and potential therapeutic targets in R-HPSCC are suggested through gene expression analysis, pathway enrichment, and intercellular communication profiling.

Zhi-Mou Cai, Jin-Hong Zhang, Yao-Dong Ding et al. · 0 citations

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