Author

Zhi-Ming Lu

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Open access Aug 2026

Therapeutic potential and underlying mechanisms of engineered young plasma-derived exosomes in Alzheimer's disease

The potential value of young plasma-derived EXOs in AD treatment is revealed for the first time and, through RVG engineering strategies and the elucidation of the RPTOR-autophagy mechanism, provides new insights for targeted therapy of neurodegenerative diseases.

Hang Chen, Yuanquan Si, Qian Cheng et al. · Bioactive Materials · 0 citations

Aug 2026

Transcriptome-wide association analysis of Alzheimer’s disease: construction and clinical validation of transcriptomic risk scores

The AD-specific transcriptomic risk scores (TRSs) developed in this study shows promising clinical utility in AD diagnosis, differential diagnosis, and risk prediction, providing valuable translational medical evidence for early screening and precision prevention of Alzheimer's disease.

Peng-Fei Zhang, Zhongqian Juan, Jia-Lin Han et al. · European Archives of Psychia... · 0 citations