Acute-on-chronic liver failure (ACLF) is an acute and severe syndrome with high mortality and limited therapeutic options. Excessive systemic inflammation, which drives hepatocyte dysfunction and programmed cell death, constitutes the hallmark feature of ACLF progression. PANoptosis, a coordinated form of apoptosis, ne...
The theoretical framework to support the clinical translation of FSP1-targeted antitumor strategies is established and the plasticity of FSP1 dependency in tumor cells in vivo is deeply analyzed.
Peng Lin, Jingzhe Ma, Zhi-Nan Chen et al.· Ferroptosis and Oxidative St...· 0 citations
Chiral amines are essential structural motifs in pharmaceuticals, fine chemicals, and bioactive natural products. Asymmetric transfer hydrogenation (ATH) of imines represents one of the most straightforward approaches to chiral amine synthesis, yet aqueous ATH of non‐activated acyclic imines remains a longstanding ch...
Gang Zhou, Hui-Fang Nie, Peng Lin et al.· Chinese journal of chemistry· 0 citations
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