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Author

Zhishui Chen

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Open access Sep 2026

Diagnostic Performance of Donor-derived Cell-free DNA Combined With Immune Activation Markers for Detecting Acute Rejection After Liver Transplantation.

BACKGROUND Accurate differentiation of acute rejection (AR) from other causes of graft dysfunction after liver transplantation remains challenging in real-world clinical practice. Although donor-derived cell-free DNA (dd-cfDNA) has emerged as a promising non-invasive biomarker of graft injury, its specificity may be li...

Xue-Chun Zhao, Bo Yang, Hong-Mei Jiang et al. · 0 citations
Review Open access Aug 2026

Autologous immune system reset for kidney allograft acceptance: mechanisms, evidence, and a testable reconstitution-window model

Autologous hematopoietic stem cell transplantation (AHSCT)-based immune system reset (ISR) is conceptually distinct from donor-hematopoietic chimerism: recipient immunity is deeply depleted and rebuilt from recipient-derived hematopoietic stem/progenitor cells, without intended donor hematopoiesis. This review evaluate...

Chunhui Lyu, Zhishui Chen, Daqiang Zhao · 0 citations

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