Author

Zhi-Wei Cai

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Open access Aug 2026

PLCE1 exacerbates the development of atherosclerosis by driving endothelial dysfunction and macrophage inflammation via targeting CTNNB1

Findings indicate that PLCE1 is an important regulator of vascular endothelial dysfunction, leading to a classical macrophage polarization switch through its interaction with CTNNB1, which collectively accelerates the development of atherosclerosis.

Wen-Lin Cheng, Yu-Fang Shi, Quan Zhang et al. · Cell Death Discovery · 0 citations