Author

Zhiwei Xia

2 papers indexed here

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Review Open access Sep 2026

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

ABSTRACT While conventional two‐dimensional (2D) cultures and animal models remain essential tools, they frequently fail to recapitulate the three‐dimensional (3D) architecture, biomechanical cues, and spatial complexity of human tumors, thereby limiting their translational relevance. To address these limitations, scaf...

Hai-Tao Zhao, Yue-Chen Han, Jie Li et al. · Advancement of science · 0 citations

Open access Aug 2026

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

ABSTRACT Background: Glioblastoma (GBM) establishes a highly immunosuppressive microenvironment through intricate molecular dialogues with tumor‐associated macrophages (TAMs), contributing to immunotherapy resistance. Methods: We integrated advanced biological network analyses with multimodal AI to identify CTSB as a k...

Hao Zhang, Nan Zhang, Xisong Liang et al. · Advancement of science · 0 citations