A Dual pH‑Responsive Hydrogel with Site‑Specific Therapeutic Functions for Differential Pathological Microenvironment Remodeling and Accelerated Repair of Infected Diabetic Wounds.
Diabetic skin wounds have disrupted local acid-base balance, prone to bacterial adhesion and sustained chronic inflammation that hinders tissue repair. Benefiting from the unique properties of oxidized sodium alginate, we prepared a dual pH-responsive Schiff base crosslinked hydrogel loaded with herbal nanoparticles to...