Author

Zhi-Xue Wang

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Open access Jul 2025

A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity

Small RNA-mediated gene silencing contributes to plant immunity. The secondary small interfering RNA (siRNA) pathway promotes defense by silencing target genes in invading fungal and oomycete pathogens. Many secondary siRNAs derive from transcripts potentially encoding pentatricopeptide repeat (PPR) proteins. Here, we...

Li Feng, Ying-Nan Hou, AmirAli Toghani et al. · bioRxiv · 3 citations

Open access Aug 2026

A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity

It is reported that siRNA production is an ancient function of a conserved clade of a conserved clade of PPR genes that undergo extensive within-species diversification and accumulation of high-impact variations including pseudogenization, leading to the accumulation of a diverse siRNA pool.

Li Feng, Yingnan Hou, AmirAli Toghani et al. · Nature Communications · 1 citation