Oct 2026
Artemether induces JNK1/FOXO1/GPX4-mediated ferroptosis to suppress colorectal cancer.
BACKGROUND Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, necessitating novel therapeutic strategies. Ferroptosis, an iron‑dependent, lipid-peroxidation-driven form of cell death, has emerged as a potential tumor‑suppressive mechanism. Artemether, a derivative of Artemisia annua...
Lv Ge, Huu-Shen Lu, Bo-Yun Zeng et al.
· Tissue & Cell · 0 citations