Author

Zhi-Yong Jiang

2 papers indexed here

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Open access Aug 2026

Regiospecific de mayo reactions of enamino ketones

The de Mayo reaction is a powerful photochemical method for skeletal editing, enabling rapid synthesis of 1,5-dicarbonyl compounds through formal addition of 1,3-dicarbonyl units across olefins. However, its regio- and chemoselectivity remain limited. Distinct aryl groups cannot be selectively installed on 1,5-diketone...

Wenxiu Zhu, Xin Sun, Dong Tian et al. · Nature Communications · 0 citations

Sep 2026

Discovery of Biaryl amide-containing transmembrane serine protease 2 (TMPRSS2) inhibitors for the treatment of prostate Cancer.

Results indicate that XDTM13 and XDTM14 are promising lead compounds for TMPRSS2 inhibition, with XDTM13 emerging as a particularly potent candidate for further development.

Zi-Jie Jin, Hao Yao, Jiang-Hui Ye et al. · Bioorganic chemistry (Print) · 0 citations