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Author

Zhi-You Yang

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Review Sep 2026

Phytocannabinoid cannabidiol (CBD) in neurodegenerative diseases: From polypharmacology to drug development.

Cannabidiol (CBD) is a non-intoxicating phytocannabinoid that has attracted interest as a multi-target neurotherapeutic candidate for neurodegenerative diseases. CBD is a lipophilic terpenophenolic chemotype whose phenolic redox chemistry, membrane partitioning, cytochrome P450-mediated metabolism, and formulation-depe...

Bing-Xing Zhang, Jiang Nan, Yun-Fei Zhang et al. · 0 citations
Open access Jul 2026

Sarsasapogenin Improves Pathological Phenotypes in MPTP/MPP+-Induced Parkinson's Disease Models: Synergistic Actions of Neurite Outgrowth, Neurotransmitter Modulation, and Anti-Inflammation.

Sarsasapogenin exerts comprehensive neuroprotective effects in preclinical PD models via synergistic modulation of dopaminergic neuronal survival, neurotransmitter balance, inflammatory inhibition, and neurite outgrowth.

Wen-Di Deng, Jin-Feng Hong, Weixia Li et al. · 0 citations

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