Author

Zhi-Yuan Yuan

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Open access Sep 2026

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

ABSTRACT Stroke remains a leading cause of long‐term neurological disability worldwide, largely due to irreversible neuronal loss and the limited regenerative capacity of the adult mammalian brain. Neural stem cells (NSCs) in the adult brain possess the potential to generate new neurons after injury, yet the molecular...

Ruo-Lin Zhang, Chang Liu, Yu-Neng Zhou et al. · Advancement of science · 0 citations

Aug 2026

The Multimodal Pretraining Framework CarHE Predicts Spatial Transcriptomics in Tumors from Routine Pathology Images.

CarHE (contrastive alignment of gene expression for hematoxylin and eosin images), a multimodal pretraining framework that infers high-dimensional spatial transcriptomic profiles from routine H&E-stained slides, provides a cost-effective and scalable framework for H&E-based spatial inference, supporting further validat...

Jiawei Zou, Kai Xiao, Ze-Xi Chen et al. · Cancer Research · 0 citations

#artificial intelligence Preprint Aug 2026

PXDepth: Pixel-Space Modeling for Structure Preserving Monocular Depth Estimation

PXDepth is a discriminative monocular depth model that separates global context modeling from pixel-level depth prediction, and combines faithful local geometry with competitive global depth accuracy while remaining efficient at inference.

Zhi-Yuan Yuan, Guanying Chen, Lingteng Qiu et al. · 1 citation