Author

Zhi-Zhen Liu

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Open access Aug 2026

Recombinant human Thymosin β4 ameliorates experimental colitis and intestinal fibrosis through suppression of mineralocorticoid receptor signaling

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder characterized by epithelial barrier disruption, persistent mucosal inflammation, and progressive intestinal fibrosis, for which effective therapeutic options remain limited. Thymosin β4 (Tβ4) is a highly conserved endogenous peptide with established ro...

Taoran Zhao, En-Bo Hu, Meng-wei Wang et al. · Molecular Biomedicine · 0 citations

Open access Sep 2026

STC2 promotes cisplatin resistance through metabolic reprogramming and lactylation-mediated epigenetic regulation in cervical cancer.

Cervical cancer (CC) is a major threat to women's health globally, and the development of cisplatin (DDP) resistance is a key factor leading to treatment failure. Prior research from our group has demonstrated the significant involvement of stanniocalcin-2 (STC2) in mediating DDP-resistance in CC. This study explores t...

Shan-Shan Jin, Dong-Qi Gao, Ya-Ling Xiahou et al. · Acta Biochimica et Biophysic... · 0 citations

Open access Sep 2026

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

It is demonstrated that SF3B1 undergoes intrinsic, IDR‐driven liquid‐liquid phase separation both in vitro and in vivo, forming nuclear condensates in oocytes and early embryos, which is essential for successful development to the blastocyst stage.

Kang Zhao, Ting-Yu Han, Yan-Li Cheng et al. · Advancement of science · 0 citations