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Author

Zhi Zheng

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2 papers indexed here

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Open access Sep 2026

Toxoplasma gondii infection disrupts secondary bile acid transformation in feline gut microbiota

ABSTRACT Bile acid (BA) transformation relies on gut microbiota and is vulnerable to Toxoplasma gondii infection, yet feline microbial BA-transforming capacity upon toxoplasmosis remains unclear. Here, we constructed a catalog of 2,474 nonredundant feline gut microbial genomes and integrated serum metabolomic data to v...

Lu-Yao Tang, He Zhang, Ji-Xin Zhao et al. · 0 citations
Open access Aug 2026

A Live Attenuated AP2X-1-Deficient Toxoplasma Strain Confers Protective Immunity Against Acute and Chronic Toxoplasmosis in a Murine Model

PruΔap2X-1 represents a potential live-attenuated vaccine candidate against toxoplasmosis, with a favorable safety profile observed under the experimental conditions, and induces a strong Th1-biased cellular and humoral immune response.

Wen-Bo Hao, Li-Xiu Sun, Ru-Shi Tu et al. · 0 citations

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